Functional characterization of WalRK: A two-component signal transduction system fromBacillus anthracis
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چکیده
منابع مشابه
Functional characterization of WalRK: A two-component signal transduction system from Bacillus anthracis☆
Two-component signal transduction systems (TCS), consisting of a sensor histidine protein kinase and its cognate response regulator, are an important mode of environmental sensing in bacteria. Additionally, they have been found to regulate virulence determinants in several pathogens. Bacillus anthracis, the causative agent of anthrax and a bioterrorism agent, harbours 41 pairs of TCS. However, ...
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Most prokaryotic signal-transduction systems and a few eukaryotic pathways use phosphotransfer schemes involving two conserved components, a histidine protein kinase and a response regulator protein. The histidine protein kinase, which is regulated by environmental stimuli, autophosphorylates at a histidine residue, creating a high-energy phosphoryl group that is subsequently transferred to an ...
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ژورنال
عنوان ژورنال: FEBS Open Bio
سال: 2014
ISSN: 2211-5463
DOI: 10.1016/j.fob.2013.12.005